Important publications

Abd Alla, J., Langer, A., Wolf, S., Fu X, Rageh MA, Quitterer U. BBLN triggers CAMK2D pathology in mice under cardiac pressure overload and potentially in unrepaired hearts with tetralogy of Fallot. external pageNat Cardiovasc Res 2023; 2:1044–1059call_made.

Abd Alla J, Nerger E, Langer A, Quitterer U. Identification of membrane palmitoylated protein 1 (MPP1) as a heart-failure-promoting protein triggered by cardiovascular risk factors and aging. external pageBiochem Pharmacol. 2023;217:115789.call_made

Quitterer U, AbdAlla S.
Pathological AT1R-B2R Protein Aggregation and Preeclampsia. external pageCells. 2021; 10(10):2609.call_made

Abd Alla J, Jamous YF, Quitterer U.
Stearoyl-CoA Desaturase (SCD) Induces Cardiac Dysfunction with Cardiac Lipid Overload and Angiotensin II AT1 Receptor Protein Up-Regulation. external pageInt J Mol Sci. 2021 Sep 13;22(18):9883.call_made

Quitterer U, AbdAlla S.
Discovery of Pathologic GPCR Aggregation. external pageFront Med (Lausanne). 2019 Jan 30;6:9.call_made

Wolf S, Abd Alla J, Quitterer U.
Sensitization of the Angiotensin II AT1 Receptor Contributes to RKIP-Induced Symptoms of Heart Failure. external pageFront Med (Lausanne). 2019 Jan 9;5:359.call_made

Quitterer U, Fu X, Pohl A, Bayoumy KM, Langer A, AbdAlla S.
Beta-Arrestin1 Prevents Preeclampsia by Downregulation of Mechanosensitive AT1-B2 Receptor Heteromers.
external pageCell. 2019 Jan 10;176(1-2):318-333.call_made

AbdAlla S, El Hakim A, Abdelbaset A, Elfaramawy Y, Quitterer U.
Inhibition of ACE Retards Tau Hyperphosphorylation and Signs of Neuronal Degeneration in Aged Rats Subjected to Chronic Mild Stress. external pageBiomed Res Int. 2015;2015:917156.call_made

Abd Alla J, Graemer M, Fu X, Quitterer U.
Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice. external pageJ Biol Chem. 2016 Feb 5;291(6):2583-600.call_made

Quitterer U, AbdAlla S.
Vasopressor meets vasodepressor: The AT1-B2 receptor heterodimer. external pageBiochem. Pharmacol. 2014, 88, 284-290.call_made

Fu X, Koller S, Abd Alla J, Quitterer U.
Inhibition of G-protein-coupled receptor kinase 2 (GRK2) triggers the growth-promoting mitogen-activated protein kinase (MAPK) pathway. external pageJ. Biol. Chem. 2013call_made, 288, 7738-7755. external pageGEO accession nocall_made. GSE42753, external pageGEO accession nocall_made. GSE42771

Abdalla J, Langer A, Elzahwy SS, Arman-Kalcek G, Streichert T, Quitterer U.
Angiotensin-converting enzyme (ACE) inhibition down regulates the pro-atherogenic chemokine receptor 9 (CCR9) - chemokine ligand 25 (CCL25) axis. external pageJ. Biol. Chem., 2010, 285, 23496-23505call_made. external pageGEO accession no. GSE19286call_made

• external pageSelected by NCBI as GEO profile (GDS3683) with presentation on 2256 pagescall_made
• http://www.ncbi.nlm.nih.gov/geoprofiles?term=GDS3683[ACCN]

AbdAlla S, Lother H, Langer A, el Faramawy Y, Quitterer U.
Factor XIIIA transglutaminase crosslinks AT1 receptor dimers of monocytes at the onset of atherosclerosis. external pageCell, 2004, 119, 343-354call_made.

• Preview: Ogawa S, Glass CK. external pageFactor XIIIA (cross)links AT1 receptors to atherosclerosis.call_made Cell, 2004, 119, 313-314.
• Commentary: Thomas WG. external pageDouble trouble for type 1 angiotensin receptors in atherosclerosis.call_made New. Engl. J. Med., 2005, 352, 506-508.
• Data added to the "Biomolecular Interaction Network Database" (BIND)

Lorenz K, Lohse MJ, Quitterer U.
PKC switches the Raf kinase inhibitor from Raf-1 to GRK-2. external pageNature, 2003, 426, 574-579call_made.

• Commentary: Goel, R., Baldassare, J. J. external pageKilling two birds with one RKIP.call_made Trends. Endocrinol. Metab., 2004, 15, 91-92.
• Data added to the "Biomolecular Interaction Network Database" (BIND)

AbdAlla S, Lother H, Massiery A, Quitterer U.
Increased AT1 receptor heterodimers in preeclampsia mediate enhanced angiotensin II responsiveness. external pageNature Medicine, 2001, 7, 1003-1009.call_made

• News and Views: Lodwick D. external pageReceptor double-trouble in preeclampsia.call_made Nature Medicine, 2001, 7, 999-1000.
• 2013: Independent confirmation of AT1-receptor heterodimers after 10 years of discussion: external pageWilson et al. J. Biol. Chem., 2013, 288, 18872-18884.call_made

AbdAlla S, Lother H, Quitterer U.
AT1-receptor heterodimers show enhanced G-protein activation and altered receptor sequestration. external pageNature, 2000, 407, 94-98call_made.

• Highly cited paper (Top 1 % of the field according to ISI Web of Science)
• 2013: Independent confirmation of AT1-receptor heterodimers after 10 years of discussion: external pageWilson et al. J. Biol. Chem., 2013, 288, 18872-18884.call_made